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Rheumatoid Arthritis

Around 1% of the UK population have been diagnosed with Rheumatoid Arthritis 1 which usually affects your joints, causing pain, swelling and stiffness, but it can also affect your organs including your lungs, heart and eyes. If either your anti-CCP or RF levels are raised, you will need to make an appointment with your GP to discuss the findings in order to make a truly positive diagnosis.

Rheumatoid Arthritis

Your test looks for anti-CPP and RF antibodies in your blood, which can help detect rheumatoid arthritis.

£29

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Rheumatoid Arthritis

Rheumatoid Arthritis usually affects your joints, causing pain, swelling and stiffness, but it can also affect your organs including your lungs, heart and eyes.

It can affect people of all ages, but the most common age for people to develop the condition is between 40 and 60.  It’s also two to three times as common in women than men. 2

Anti-CPP and RF can be used to help detect rheumatoid arthritis, but the tests aren’t accurate for everyone. Around 1 in 20 individuals without rheumatoid arthritis will test positive for RF and not everyone with rheumatoid arthritis will have raised anti-CPP levels.  Positive test for both RF and anti-CCP may be more likely to have severe rheumatoid arthritis requiring higher levels of treatment 3

Dr Cullimore says “Rheumatoid Arthritis is an autoimmune disease, meaning your immune system mistakenly attacks the lining of your joints (the synovial lining).  This damage to the lining of your joints causes inflammation, leading to symptoms of pain, swelling and stiffness.  People with rheumatoid arthritis tend to have a higher risk of heart disease and stroke; with the availability of sophisticated therapies and drugs, it is important to diagnose and treat the disease early to avoid long-term damage.”


Rheumatoid arthritis. Clinical Knowledge Summaries. January 2019: https://cks.nice.org.uk/rheumatoid-arthritis#!topicSummary

2 Rheumatoid arthritis in adults: management. NICE guideline [NG100] Published date: https://www.nice.org.uk/guidance/ng100/chapter/Context

3 NHS Rheumatoid arthritis. https://www.nhs.uk/conditions/rheumatoid-arthritis/diagnosis/

All our tests have been specially designed to be convenient and non-invasive. Once you’ve booked your appointment, full preparation instructions will be provided in your confirmation email or letter. You can continue to eat and drink normally before your appointment, and you’ll also remain fully clothed throughout.

Which readings are included?

RF are proteins produced by your immune system that can attack healthy tissue in your body. If either your anti-CCP or RF levels are raised, you will need to make an appointment with your GP to discuss the findings in order to make a truly positive diagnosis.
Anti-CCP is an antibody present in most people with rheumatoid arthritis. If either your anti-CCP or RF levels are raised, you will need to make an appointment with your GP to discuss the findings in order to make a truly positive diagnosis.

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